Tag Archives: leptin

Leptin: The Secret Behind its Affect on Weight Loss

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Only then will you be able to enjoy long-term ideal weight. Here, we’ll take a look at the role leptin plays in all of this. Leptin and Obesity One of the most important hormones responsible for hunger, metabolism, reproduction, fat management and energy production is leptin. Leptin is made by fat cells in proportion to body fat mass, so more body fat means you’ll be producing more leptin. Without proper leptin response, you will not feel satisfied from your meals. In overweight people, there is an increase of fat mass and a corresponding increase in circulating leptin. In such cases the appropriate response of reducing food intake and increasing energy expenditure doesn’t happen, and this suggests a state of leptin resistance. This leptin resistance results in a leptin deficiency in the hypothalamus and so multiple mechanisms are activated to increase fat stores, as the body perceives this as a state of starvation. Inflammation […]

13 Numbers About Your Health That You Need To Know

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2.5 OR LOWER Thyroid Stimulating Hormone (TSH) levels above 2.5 are considered to be suspicious for subclinical hypothyroidism by many integrative physicians. The “normal” reference range for the TSH test tends to run from .3 to 4.5, and many patients with levels above 2.5 are told their thyroid is “normal,” while their physicians fail to test to actual circulating thyroid hormone (Free T4, Free T3) or the thyroid antibodies that can detect an autoimmune thyroid disease. 1.3 OR HIGHER The Free T4 test measures the available amount of the T4 storage hormone available to be converted into T3, the active thyroid hormone. While the reference range at many labs runs from .8 to 2.8 ng/dL, integrative physicians have found that most patients feel best when their level falls into the top half of the range, at a level of 1.3 or higher. 3.2 OR HIGHER The Free T3 test measures […]

7 Signs That You Need a New Doctor

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To borrow the metaphor, you may have to kiss a few frogs along the way before you find that prince — or princess — or a practitioner. But in some cases, it becomes clear that this is not a working relationship, and it’s time to move on. Here are seven signs that you definitely need a new doctor. 1. Your Doctor Questions Whether Fibromyalgia, Chronic Fatigue Syndrome or Adrenal Insufficiency Are “Real” Diagnoses If you get an inkling that your doctor lumps Fibromyalgia and Chronic Fatigue Syndrome — as well as adrenal insufficiency — into the category of psychosomatic, somatoform illnesses, or suggests that they are somehow not real, “made-up,” “trendy,” or in your head, it’s a clear warning that you need a new doctor. Move on to a more knowledgeable practitioner who is up on the latest research and findings about these conditions. 2. Your Doctor Bristles at the Word “Bioidentical” […]

Weight Gain Despite Thyroid Treatment May Be Hypothalamic Obesity Disorder

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The research was presented in a poster session by Saad Sakkal, MD at the May 2014 annual meeting of the American Association of Clinical Endocrinologists (AACE). Before we take a look at the research, let’s explain a bit more about the hypothalamus and its impact on weight and metabolism. What is The Hypothalamus? Your hypothalamus is an almond-sized part of the brain that connects your nervous system to your endocrine system, with your pituitary gland acting as a go-between. The job of the hypothalamus is to release hormones that then cause the pituitary gland to release (or stop releasing) pituitary hormones. This hormonal process controls the body’s temperature, hunger, thirst, fatigue, sleep cycles, and daily cyclical rhythms. Cells in the hypothalamus take up the inactive form of thyroid hormone T4 (thyroxine), and convert the T4 into the active thyroid hormone, T3 (triiodothyronine.) The T3 then stimulates the production of TSH, […]

Tips for Losing Weight With Thyroid Problems

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Losing weight with thyroid problems can be a difficult task. Therefore, thyroid patients need to know more about factors that are likely at work contributing to weight loss challenges — a changed metabolic “set point;” two key hormones: leptin and reverse T3; changes in brain chemistry due to illness or stress; and insulin resistance. Metabolic Set Point The basic premise of the set-point theory is that the body has a built in weight regulating mechanism that will tend to keep your weight in a physiologically established comfortable range. Have you felt that despite initial weight loss success, your body will tend to go back to your “normal” increased weight, despite significantly reducing calories and/or increasing exercise? Just like your body works to maintain a temperature “set point” of 98.6, it also appears to work toward maintaining a particular weight “set point.” There are numerous medications that can result in an increase in the body’s weight […]