We specialize in thyroid optimization with T4/T3 combination’s and straight T3 and treat all types of hypothyroidism, including standard (primary), secondary (pituitary dysfunction), tertiary (hypothalamic), which result in normal or low TSH with sub-optimal T4 and T3 levels, low T3 syndromes, poor conversion of T4 to T3, high reverse T3 (Wilson’s syndrome), thyroid receptor resistance syndromes, which results in hypothyroidism with normal thyroid blood levels, difficult thyroid cases. Patients fly in from all over the United States for thyroid treatment.
Have You Been Told Your Thyroid is Normal?
New, better test is now available through our office to accurately determine your thyroid hormone levels.
Common Complaint: I’ve been told my thyroid is normal, but I still suffer with symptoms of a low thyroid…
Fatigue- Difficulty Losing Weight
- Depression
- Body Aches
- Low Libido
- Cold all the Time
- Water Retention
- Dry Skin, Eczema
- No Relief from my Treatment for Chronic Fatigue Syndrome, Fibromyalgia PMS, or Menopause
- Diffuse Hair Loss or dry hair
- Cold extremities
- Constipation
- Poor memory
- Poor concentration
- Anxiety
- Weakness
- Pale skin
- Shortness of breath
- Palpitations
- PMS
- Heavy menstrual flow
- Muscle or joint aches
- Poor motivation
Diagnosis of hypothyroidism: Are we getting what we want from TSH testing?
Hypothyroidism is a common disorder where there is inadequate cellular thyroid effect to meet the needs of the tissues. Typical symptoms of hypothyroidism include fatigue, weight gain, depression, cold extremities, muscle aches, headaches, decreased libido, weakness, cold intolerance, water retention, premenstrual syndrome (PMS) and dry skin. Low thyroid causes or causes or contributes to the symptoms of many conditions can but the deficiency is often missed by standard thyroid testing.[...]
Why Doesn’t My Endocrinologist Know All of This?
A question often raised by patients is: “Why doesn’t my physician know about the inaccuracies and limitations of standard thyroid tests?” The reason is that the overwhelming majority of physicians (endocrinologists, internists, family practitioners, rheumatologists, etc.) do not read medical journals. When asked, most doctors will claim that they routinely read medical journals, but this has been shown not to be the case. [...]
Fatigued, depressed, difficulty losing weight..?
An understanding of the alterations in serum thyroid levels in the presence of stress, illness, depression, calorie reduction or aging allows for an accurate diagnosis of cellular hypothyroidism and explains why the TSH is an unreliable and inaccurate measure of cellular hypothyroidism
Unique pituitary physiology results in inaccuracy of TSH testing…
Age dependent variations in mean serum levels of Free T4 (A), Free T3 (B) and TSH (C) in healthy individuals-a combined analysis of the literature. Demonstrates that TSH is not a reliable marker of active thyroid (T3) levels (low T3 levels are associated with decreased, not increased, TSH levels).
Why Standard Blood Tests Lack Sensitivity to Detect Low Tissue Thyroid Levels
It may be due to your hormones Since the endocrine system is devised
of glands that produce and send hormones to all areas of our body to
regulate the essential functions of our body like temperature,
reproduction, growth, immunity, and aging, it stands to reason that this
should be the hub of vitality, longevity and well [...]
Thyroid Physiology
See detailed image.
[...]
Reverse T3 is the Best Measurement of Tissue Thyroid Levels
The Journal of Clinical Endocrinology & Metabolism 2005;
90(12):6403-6409 Thyroid Hormone Concentrations, Disease, Physical Function
and Mortality in Elderly Men Annewieke W. van den Beld, Theo J. Visser,
Richard A. Feelders, Diederick E. Grobbee, and Steven W. J. Lamberts
Department of Internal Medicine (A.W.v.d.B., T.J.V., R.A.F., S.W.J.L.),
Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; [...]
Been told your thyroid is normal despite having symptoms of low thyroid?
The British Medical Journal 326:311-2 Serum TSH in assessment of
severity of tissue hypothyroidism in patients with overt primary thyroid
failure: cross sectional survey Meier C, Trittibach P, Guglielmetti M,
Staub JJ, Muller B. In 49 patients with primary hypothyroidism, the authors
investigated the correlation of TSH, free T4 and T3 with the level of
tissue hypothyroidism (thyroid [...]
Standard thyroid tests lack accuracy to determine proper dose of thyroid replacement
The British Medical Journal 293:808-810 Are biochemical tests of
thyroid function of any value in monitoring patients receiving thyroxine
replacement? Fraser WD, Biggart EM, OReilly DJ, Gray HW, McKillop JH Most
physicians, including endocrinologists, rely on standard thyroid tests to
determine their patients’ “proper” dose of thyroid replacement. The
evaluation of a patient’s signs and symptoms [...]
Tissue and pituitary levels of T3 with T4 only preparations
Journal of Clinical Investigation 96:2828-2838 Replacement therapy for
hypothyroidism with thyroxine alone does not ensure euthyroidism in all
tissues… Escobar-Morreale HF, Obregon MJ, Escobar del Rey F, Morreale de
Escobar G Levothyroxine (T4) only replacement with products such as
Synthroid and Levoxyl are the most widely accepted forms of thyroid
replacement. This is based on a [...]
Reduced Metabolic Rate with Dieting
American Journal of Clinical Nutrition, Vol 44, 585-595 Adaptation of
energy metabolism of overweight women to low energy intake, studied with
whole-body calorimeters Jo de Boer, AJ van Es, LC Roovers, JM van Raaij and
JG Hautvast In 14 overweight women, 24-hour energy expenditure (EE) was
measured in a whole-body indirect calorimeter: before weight reduction
(100% [...]
Diet Induced Thyroid Suppression
Journal of Clinical Endocrinology & Metabolism,
doi:10.1210/jc.2005-0920 High circulating Thyrotropin levels in obese women
are reduced after body weight loss induced by caloric restriction Petra
Kok, Ferdinand Roelfsema, Janneke G. Langendonk, Marijke Frölich,
Jacobus Burggraaf, A. Edo Meinders and Hanno Pijl Context: Previous
clinical studies concerning the impact of body weight loss on single plasma
TSH concentration [...]
Low Normal Thyroid Levels Cause Weight Gain
The Journal of Clinical Endocrinology & Metabolism 90(7):4019-4024
Small Differences in Thyroid Function May Be Important for Body Mass Index
and the Occurrence of Obesity in the Population Nils Knudsen, Peter
Laurberg, Lone B. Rasmussen, Inge Bu¨ low, Hans Perrild, Lars Ovesen,
and Torben Jørgensen This study demonstrates that low normal thyroid
levels are associated [...]
Reverse T3 Suppresses T4 to T3 Conversion
Endocrinology 101(2):453-63 A study of extrathyroidal conversion of
thyroxine (T4)to 3,3′,5-triiodothyronine (T3) in vitro Chopra IJ Most
endocrinologists believe that reverse T3 (rT3) is just and inactive
metabolite with no physiologic effect, which is not the case, however. This
study and subsequent others demonstrate that rT3 is a more potent inhibitor
of T4 to T3 conversion than [...]
Thyrotropin Suppression by Metformin
The Journal of Clinical Endocrinology & Metabolism; 91(1):225-227
Thyrotropin Suppression by Metformin Robert A. Vigersky, Amy
Filmore-Nassar, and Allan R. Glass Endocrinology Service, Walter Reed Army
Medical Center, Washington, DC 20307 This study noted that patients on
metformin (Glucohage) had a subsequent suppression in TSH level without a
change in serum thyroid levels, demonstrating that there is [...]
The Learning Channel
Dr. Holtorf discussed the controversies and inadequacies of standard
thyroid testing on The Learning Channel airing in January, 2007. He
demonstrated this fact with a case study patient brought to see Dr. Holtorf
by The Learning Channel. This patient had extreme difficulty losing weight
even after having gastric bypass surgery and suspected she had low [...]
Additional Studies
Low normal thyroid levels result in a higher risk of heart disease
than if you have high cholesterol, high blood pressure, if you smoke or
even have diabetes. Individuals with low normal thyroid levels are 2.5
times more likely to suffer a heart attack. This is greater than if you
have high cholesterol (2.4 times [...]
Endocrinological Assessment and Treatment of Obesity
Obesity has become a major health epidemic and has dramatically
increased over the last decades. Studies show that now approximately
one-third of the U.S. population is classified as obese and over two-thirds
are significantly overweight. While the cause is multifactorial, studies
are clear that almost all overweight individuals have metabolic and
endocrinological dysfunction that is [...]
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